A Human-Centered Approach to Identifying Promises, Risks, & Challenges of Text-to-Image Generative AI in Radiology

Authors

  • Katelyn Morrison Carnegie Mellon University
  • Arpit Mathur Carnegie Mellon University
  • Aidan Bradshaw Carnegie Mellon University
  • Tom Wartmann ETH Zurich
  • Steven Lundi UCLA Health
  • Afrooz Zandifar UPMC
  • Weichang Dai Boston University
  • Kayhan Batmanghelich Boston University
  • Motahhare Eslami Carnegie Mellon University
  • Adam Perer Carnegie Mellon University

DOI:

https://doi.org/10.1609/aies.v8i2.36672

Abstract

As text-to-image generative models rapidly improve, AI researchers are making significant advances in developing domain-specific models capable of generating complex medical imagery from text prompts. Despite this, these technical advancements have overlooked whether and how medical professionals would benefit from and use text-to-image generative AI (GenAI) in practice. By developing domain-specific GenAI without involving stakeholders, we risk the potential of building models that are either not useful or even more harmful than helpful. In this paper, we adopt a human-centered approach to responsible model development by involving stakeholders in evaluating and reflecting on the promises, risks, and challenges of a novel text-to-CT Scan GenAI model. Through exploratory model prompting activities, we uncover the perspectives of medical students, radiology trainees, and radiologists on the role that text-to-CT Scan GenAI can play across medical education, training, and practice. This human-centered approach additionally enabled us to surface technical challenges and domain-specific risks of generating synthetic medical images. We conclude by reflecting on the implications of medical text-to-image GenAI.

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Published

2025-10-15

How to Cite

Morrison, K., Mathur, A., Bradshaw, A., Wartmann, T., Lundi, S., Zandifar, A., … Perer, A. (2025). A Human-Centered Approach to Identifying Promises, Risks, & Challenges of Text-to-Image Generative AI in Radiology. Proceedings of the AAAI ACM Conference on AI, Ethics, and Society, 8(2), 1758–1770. https://doi.org/10.1609/aies.v8i2.36672