PD Disease State Assessment in Naturalistic Environments Using Deep Learning


  • Nils Hammerla Newcastle University
  • James Fisher Health Education North East
  • Peter Andras Keele University,
  • Lynn Rochester Newcastle University
  • Richard Walker Northumbria Healthcare NHS Foundation Trust
  • Thomas Ploetz Newcastle University,




Deep learning, Parkinson's Disease, Accelerometer, Naturalistic Environments


Management of Parkinson's Disease (PD) could be improved significantly if reliable, objective information about fluctuations in disease severity can be obtained in ecologically valid surroundings such as the private home. Although automatic assessment in PD has been studied extensively, so far no approach has been devised that is useful for clinical practice. Analysis approaches common for the field lack the capability of exploiting data from realistic environments, which represents a major barrier towards practical assessment systems. The very unreliable and infrequent labelling of ambiguous, low resolution movement data collected in such environments represents a very challenging analysis setting, where advances would have significant societal impact in our ageing population. In this work we propose an assessment system that abides practical usability constraints and applies deep learning to differentiate disease state in data collected in naturalistic settings. Based on a large data-set collected from 34 people with PD we illustrate that deep learning outperforms other approaches in generalisation performance, despite the unreliable labelling characteristic for this problem setting, and how such systems could improve current clinical practice.




How to Cite

Hammerla, N., Fisher, J., Andras, P., Rochester, L., Walker, R., & Ploetz, T. (2015). PD Disease State Assessment in Naturalistic Environments Using Deep Learning. Proceedings of the AAAI Conference on Artificial Intelligence, 29(1). https://doi.org/10.1609/aaai.v29i1.9484



Main Track: Machine Learning Applications